Synthesis of N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one, a novel compound with anti-hepatitis C virus activity.
Synthesis of N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one, a novel compound with anti-hepatitis C virus activity.
复制标题
N3,5-环-4-(β-D-呋喃核糖基)-vic-三唑并[4,5-b]吡啶-5-酮的合成，一种具有抗丙型肝炎病毒活性的新型化合物。
DOI：
10.1021/jm0401210
复制
发表时间：
2004
影响因子：
7.3
通讯作者：
Watanabe,KyoichiA
中科院分区：
文献类型：
--
作者：
Wang,Peiyuan;Hollecker,Laurent;Pankiewicz,KrzysztofW;Patterson,StevenE;Whitaker,Tony;McBrayer,TamaraR;Tharnish,PhillipM;Sidwell,RobertW;Stuyver,LievenJ;Otto,MichaelJ;Schinazi,RaymondF;Watanabe,KyoichiA
A novel anti-hepatitis C virus (HCV) agent,N3,5‘-cyclo-4-(β-d-ribofuranosyl)-vic-triazolo[4,5-b]pyridinin-5-one, was identified, and the structure was confirmed by chemical synthesis from 2-hydroxy-5-nitropyridine.
