Community-based physical activity interventions for treatment of type 2 diabetes: a systematic review with meta-analysis.
Community-based physical activity interventions for treatment of type 2 diabetes: a systematic review with meta-analysis.
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DOI：
10.3389/fendo.2013.00003
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发表时间：
2013-01-01
影响因子：
5.2
通讯作者：
Lubans, David R
中科院分区：
文献类型：
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作者：
Plotnikoff, Ronald C;Costigan, Sarah A;Lubans, David R
有证据表明，定期参加体育锻炼(PA)对成年2型糖尿病(TD2)患者有好处，包括减肥、减少用药和改善血红蛋白A1c(HbA1c)/空腹血糖。虽然存在一些基于临床的PA干预措施，但基于社区的方法是有限的。本研究的目的是用荟萃分析进行系统回顾，以评估以社区为基础的PA干预对成人TD2治疗的有效性。在几个电子数据库中搜索了2002年至2012年6月期间经过同行评审的出版物，以确定在社区环境中评估的干预措施。确定了22项研究，11项报告HbA1c作为结果衡量标准的研究被汇集到荟萃分析中。同时还进行了偏倚风险评估。研究结果表明，以社区为基础的PA干预可以有效地产生PA的增加。Meta分析显示HbA1c水平下降-0.32%[95%CI-0.65，0.01]，接近统计学意义(P
Evidence suggests engaging in regular physical activity (PA) can have beneficial outcomes for adults with type 2 diabetes (TD2), including weight loss, reduction of medication usage and improvements in hemoglobin A1c (HbA1c)/fasting glucose. While a number of clinical-based PA interventions exist, community-based approaches are limited. The objective of this study is to conduct a systematic review with meta-analysis to assess the effectiveness of community-based PA interventions for the treatment of TD2 in adult populations. A search of peer-reviewed publications from 2002 to June 2012 was conducted across several electronic databases to identify interventions evaluated in community settings. Twenty-two studies were identified, and 11 studies reporting HbA1c as an outcome measure were pooled in the meta-analysis. Risk of bias assessment was also conducted. The findings demonstrate community-based PA interventions can be effective in producing increases in PA. Meta-analysis revealed a lowering of HbA1c levels by -0.32% [95% CI -0.65, 0.01], which approached statistical significance (p