BioLayout(Java): versatile network visualisation of structural and functional relationships.
BioLayout(Java): versatile network visualisation of structural and functional relationships.
复制标题
DOI：
10.2165/00822942-200504010-00009
复制
发表时间：
2005-01-01
期刊：
影响因子：
--
通讯作者：
Ouzounis, Christos A
中科院分区：
文献类型：
--
作者：
Goldovsky, Leon;Cases, Ildefonso;Ouzounis, Christos A
生物网络的可视化正在成为高通量数据分析的常见任务。这些网络对应于各种各样的生物学关系，例如序列相似性、代谢途径、基因调控级联和蛋白质相互作用。我们提出了一个通用的方法表示和分析网络的可变类型，大小和复杂性。该应用程序基于原始BioLayout程序（Fruchterman-Rheingold布局算法的C语言实现），完全用Java重写，以保证跨平台的可移植性。BioLayout（Java）提供了更广泛的功能，各种分析技术，更好的可视化扩展和新的用户界面。使用BioLayout（Java）的生物网络分析的例子。
Visualisation of biological networks is becoming a common task for the analysis of high-throughput data. These networks correspond to a wide variety of biological relationships, such as sequence similarity, metabolic pathways, gene regulatory cascades and protein interactions. We present a general approach for the representation and analysis of networks of variable type, size and complexity. The application is based on the original BioLayout program (C-language implementation of the Fruchterman-Rheingold layout algorithm), entirely re-written in Java to guarantee portability across platforms. BioLayout(Java) provides broader functionality, various analysis techniques, extensions for better visualisation and a new user interface. Examples of analysis of biological networks using BioLayout(Java) are presented.