PHYSICAL-ACTIVITY AS AN INDEX OF HEART ATTACK RISK IN COLLEGE ALUMNI

PHYSICAL-ACTIVITY AS AN INDEX OF HEART ATTACK RISK IN COLLEGE ALUMNI
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DOI:
10.1093/oxfordjournals.aje.a112608
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发表时间:
1978-01-01
影响因子:
5
通讯作者:
HYDE, RT
HYDE, RT
中科院分区:
医学2区
文献类型:
--
作者:
PAFFENBARGER, RS;WING, AL;HYDE, RT

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在117680人年的随访中,16936名年龄在35 - 74岁的哈佛男性校友中有572人发生了心脏病发作,其首次心脏病发作的风险与所报告的能量消耗呈负相关。爬楼梯、步行街区、进行剧烈运动以及综合体力活动指数都与风险呈负相关。指数低于2000千卡/周的男性比指数较高的同学患心脏病的风险高64%。成年人的运动与其他影响心脏病发作风险的因素无关,而剧烈运动等高强度活动增强了总能量消耗的效果。值得注意的是,校友的体力活动取代了16 - 50年前在大学时评估的学生运动能力。如果校队运动员身份意味着有选择性的心血管健康,那么仅这种选择不足以解释成年后期较低的心脏病发作风险。只有当退役校队运动员作为校友保持较高的体力活动指数时,他们才保留较低的风险。
Risk of 1st heart attack was related inversely to energy expenditure reported by 16,936 Harvard male alumni, aged 35-74 yr, of whom 572 experienced heart attacks in 117,680 person-years of followup. Stairs climbed, blocks walked, strenuous sports played and a composite physical activity index all opposed risk. Men with index below 2000 kc/wk were at 64% higher risk than classmates with higher index. Adult exercise was independent of other influences on heart attack risk, and peak exertion as strenuous sports play enhanced the effect of total energy expenditure. Notably, alumni physical activity supplanted student athleticism assessed in college 16-50 yr earlier. If varsity athlete status implies selective cardiovascular fitness, such selection alone is insufficient to explain lower heart attack risk in later adult years. Ex-varsity athletes retained lower risk only if they maintained a high physical activity index as alumni.