Distribution, incidence of malignant transformation, and rate of recurrence
Distribution, incidence of malignant transformation, and rate of recurrence
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分布、恶变发生率及复发率
DOI：
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发表时间：
1986
影响因子：
3.9
通讯作者：
G. Schmidt
中科院分区：
文献类型：
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作者：
M. Wegener;G. Börsch;G. Schmidt
282 名患者中，731 个结肠息肉（643 个腺瘤和 88 个增生性息肉）通过内镜摘除或活检并进行组织学研究。确定具有不同程度异型性的腺瘤和增生性息肉的定位及其大小分布。在 66 例首次检查时进行腺瘤息肉切除术的患者中，进行了一次或多次对照结肠镜检查（总共 107 例）。中位随访观察期为 31 个月。息肉切除术后一年对照结肠镜检查中有百分之三十发现新的腺瘤。统计分析表明，在初步调查中，单一腺瘤患者在进一步的病程中，与多个初始发现的患者相比，在进一步的病程中出现的腺瘤明显较少，特别是在一年对照的阴性结果中。息肉切除术后 24 个月内发现的新腺瘤大小不超过 10 毫米。根据这些结果和迄今为止可用的文献数据，提出了后续计划以供讨论。
In 282 patients, 731 colon polyps (643 adenomas and 88 hyperplastic polyps) were extirpated endoscopically or biopsied and investigated histologically. Localization of the adenomas with various degrees of atypia and the hyperplastic polyps, as well as their size distribution, were determined. In 66 patients with adenoma polypectomy on the first examination, one or more control colonoscopies were carried out (in all, 107). The median period of follow-up observation was 31 months. Thirty percent of the one-year control colonoscopies after polypectomy revealed new adenomas. The statistical analyses showed that patients with singular adenomas, on initial investigation, develop significantly fewer adenomas in the further course than patients with multiple initial findings, especially in negative results in the one-year control. The size of new adenomas found during the first 24 months after polypectomy does not exceed 10 mm. On the basis of these results and the literature data available so far, a follow-up program is presented for discussion.