Subtyping method for Escherichia coli Shiga toxin (verocytotoxin) 2 variants and correlations to clinical manifestations
Subtyping method for Escherichia coli Shiga toxin (verocytotoxin) 2 variants and correlations to clinical manifestations
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DOI：
10.1128/jcm.02591-06
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发表时间：
2007-06-01
影响因子：
9.4
通讯作者：
Scheutz, Flemming
中科院分区：
文献类型：
--
作者：
Persson, Soren;Olsen, Katharina E. P.;Scheutz, Flemming
通过对志贺毒素产生菌的志贺毒素2(Stx2)操纵子的部分测序，对志贺毒素2(Stx2)进行亚型分析。在来自丹麦STEC队列的255株菌株中，所有20例溶血性尿毒症综合征患者都与Stx2亚型(11例)、Stx2c亚型(1例)或两者兼有(8例)有关。
Shiga toxin 2 (Stx2) from Shiga toxin-producing Escherichia coli (STEC) was subtyped by a method involving partial sequencing of the stxAB(2) operon. Of 255 strains from the Danish STEC cohort, all 20 cases of hemolytic-uremic syndrome were associated with subtype Stx2 (11 cases), subtype Stx2c (1 case), or the two combined (8 cases).