Incidence of Acute Postoperative Endophthalmitis after Cataract Surgery A Nationwide Study in France from 2005 to 2014
Incidence of Acute Postoperative Endophthalmitis after Cataract Surgery A Nationwide Study in France from 2005 to 2014
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DOI：
10.1016/j.ophtha.2016.02.019
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发表时间：
2016-07-01
期刊：
影响因子：
13.7
通讯作者：
Quantin, Catherine
中科院分区：
文献类型：
--
作者：
Creuzot-Garcher, Catherine;Benzenine, Eric;Quantin, Catherine
目的：报告2005年至2014年法国白内障手术后急性术后眼内炎（POE）的发病率。设计：队列研究。参与者：接受超声乳化白内障手术并出现急性POE的患者。方法：我们通过以下方法确定了超声乳化白内障手术后6周内发生的急性POE，并在手术过程中使用前房内抗生素注射，结果：从2005年1月至2014年12月，共有3983525例患者的6371242只眼接受了超声乳化白内障手术。在这10年期间，超声乳化术后急性POE的发生率从0.145%降至0.053%;未校正的发生率比（IRR）（95%置信区间）为0.37（0.32e0.42; P < 0.001）。在多变量分析中，前房内抗生素注射与急性POE风险较低相关0.53（0.50-0.57; P < 0.001），而术中后囊膜破裂、联合手术和性别（男性）与急性POE的风险较高相关：5.24（4.11-6.68）、1.77（1.53-2.05）和1.48（1.40-1.56）（P < 0.001）。结论：通过访问国家数据库，我们观察到2005年至2014年超声乳化白内障手术后急性POE减少。在同一时期，在外科手术过程中前房内抗生素的使用增加。(C)2016年美国眼科学会。
Purpose: To report the incidence of acute postoperative endophthalmitis (POE) after cataract surgery from 2005 to 2014 in France.Design: Cohort study.Participants: Patients undergoing operation for cataract surgery by phacoemulsification and presenting acute POE.Methods: We identified acute POE occurring within 6 weeks after phacoemulsification cataract surgery and the use of intracameral antibiotic injection during the surgical procedure by means of billing codes from a national database.Main Outcome Measures: Incidence of acute POE.Results: From January 2005 to December 2014, 6 371 242 eyes in 3 983 525 patients underwent phacoemulsification cataract surgery. The incidence of acute POE after phacoemulsification decreased from 0.145% to 0.053% during this 10-year period; the unadjusted incidence rate ratio (IRR) (95% confidence interval) was 0.37 (0.32e0.42; P < 0.001). In multivariate analysis, intracameral antibiotic injection was associated with a lower risk of acute POE 0.53 (0.50-0.57; P < 0.001), whereas intraoperative posterior capsule rupture, combined surgery, and gender (male) were associated with a higher risk of acute POE: 5.24 (4.11-6.68), 1.77 (1.53-2.05), and 1.48 (1.40-1.56) (P < 0.001), respectively.Conclusions: Access to a national database allowed us to observe a decrease in acute POE after phacoemulsification cataract surgery from 2005 to 2014. Within the same period, the use of intracameral antibiotics during the surgical procedures increased. (C) 2016 by the American Academy of Ophthalmology.