Single electron transfer approaches to the practical synthesis of aromatic and heterocyclic-CF2H derivatives
Single electron transfer approaches to the practical synthesis of aromatic and heterocyclic-CF2H derivatives
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DOI：
10.1016/s0040-4039(01)00873-5
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发表时间：
2001-07-16
影响因子：
1.8
通讯作者：
Ait-Mohand, S
中科院分区：
文献类型：
--
作者：
Dolbier, WR;Médebielle, M;Ait-Mohand, S
采用单电子转移(SET)方法对一系列卤代二氟甲基化芳烃和杂环进行了单电子转移(SET)反应，并合成了相应的二氟甲基化衍生物。(C)2001爱思唯尔科学有限公司。保留所有权利。
Single electron transfer (SET) approaches with organic reductants such as sodium hydroxymethanesulfinate (Rongalite((R))), sodium dithionite (regarded as precursors of sulfoxylate radical anion) and tetrakis(dimethylamino)ethylene (TDAE) were employed for the reductive dehalogenation of a series of halogeno-difluoromethylated aromatics and heterocycles, and for the practical synthesis of the corresponding difluoromethylated derivatives. (C) 2001 Elsevier Science Ltd. All rights reserved.