Relationship between postural change of the intraocular pressure and visual field loss in primary open-angle glaucoma
Relationship between postural change of the intraocular pressure and visual field loss in primary open-angle glaucoma
复制标题
DOI：
10.1097/00061198-200308000-00015
复制
发表时间：
2003-08-01
影响因子：
2
通讯作者：
Shiraga, F
中科院分区：
文献类型：
--
作者：
Hirooka, K;Shiraga, F
目的：目的：探讨原发性开角型青光眼患者体位性眼压变化与视野损害的关系。在坐位和仰卧位测量眼内压。视野测量与自动perimetry.Results：当患者从坐位到仰卧位，眼内压平均增加3.1 +/- 0.4毫米汞柱（平均值+/- SEM）在正常人和4.0 +/- 0.2毫米汞柱原发性开角型青光眼患者。原发性开角型青光眼患者与正常人比较，差异有统计学意义（P = 0.049）。平均偏差较差眼的眼压增加4.4 +/- 0.3 mm Hg（P = 0.02），平均偏差较好眼的眼压增加3.6 +/- 0.3 mm Hg（P = 0.38）。两组之间的坐位眼压无显着差异。结论：坐位和仰卧位之间的眼压差异最大，观察到在原发性开角型青光眼患者的眼睛较差。这一结果表明，原发性开角型青光眼的视神经损伤可能发生在患者仰卧位睡眠时。
Purpose: To determine the relationship between the postural changes of the intraocular pressure and the visual field loss in patients with primary open-angle glaucoma.Methods: Eleven normal subjects and I11 patients with primary open-angle glaucoma were studied. Intraocular pressure was measured in both the sitting and the supine positions. Visual fields were measured with automated perimetry.Results: When patients moved from a sitting to supine position, the intraocular pressure increased by an average of 3.1 +/- 0.4 mm Hg (mean +/- SEM) in normal subjects and 4.0 +/- 0.2 mm Hg in patients with primary open-angle glaucoma. There was a significant difference between the normal subjects and patients with primary open-angle glaucoma (P = 0.049). Intraocular pressure increased by 4.4 +/- 0.3 mm Hg (P = 0.02) in the worse eye for mean deviation and 3.6 +/- 0.3 mm Hg (P = 0.38) in the better eye for mean deviation. There was no significant difference in intraocular pressure in the sitting position between both groups.Conclusions: The greatest difference in intraocular pressure between the sitting and supine positions was observed in the worse eye of patients with primary open-angle glaucoma. This result suggests that damage to the optic nerve in primary open-angle glaucoma might occur when patients are asleep in the supine position.