The role of particles in the pathogenesis of joint disease.
The role of particles in the pathogenesis of joint disease.
复制标题
颗粒在关节疾病发病机制中的作用。
DOI：
10.1007/978-3-642-68382-4_7
复制
发表时间：
1982
期刊：
影响因子：
--
通讯作者：
M. Doherty
中科院分区：
文献类型：
--
作者：
P. Dieppe;M. Doherty
已知损伤滑膜关节的损伤数量有限。它们包括机械紊乱、感染性微生物、改变细胞代谢的代谢因素、免疫刺激和关节颗粒。本章回顾了关节内颗粒在许多关节疾病的发病机制中发挥作用的证据，并探讨了颗粒诱导损伤的可能机制。
There are a limited number of known insults which damage synovial joints. They include mechanical derangement,infective organisms, metabolic factors altering cellular metabolism, immunological stimuli and joint particles. This chapter reviews the evidence that intra-articular particles play a role in the pathogenesis of many joint diseases and explores possible mechanisms of particle-induced damage.