Grit and the brain: spontaneous activity of the dorsomedial prefrontal cortex mediates the relationship between the trait grit and academic performance.
Grit and the brain: spontaneous activity of the dorsomedial prefrontal cortex mediates the relationship between the trait grit and academic performance.
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毅力和大脑：背内侧前额叶皮层的自发活动介导毅力特质与学业成绩之间的关系
DOI：
10.1093/scan/nsw145
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发表时间：
2017-03-01
影响因子：
4.2
通讯作者：
Gong Q
中科院分区：
文献类型：
--
作者：
Wang S;Zhou M;Chen T;Yang X;Chen G;Wang M;Gong Q
摘要坚毅作为一种人格特质，是指以持续的激情和毅力努力实现长期目标的倾向，在个人成就中起着极其重要的作用。然而，砂砾的神经机制在很大程度上仍然未知。在这项研究中，我们的目的是探讨砂砾和低频波动（fALFF）的分数振幅之间的关联在217名健康的青少年学生使用静息态功能磁共振成像（RS-fMRI）。我们发现，一个人的砂砾是负相关的区域fALFF在右背内侧前额叶皮层（DMPFC），这是参与自我调节，规划，目标设定和维护，以及反事实思维反思过去的失败。即使在调整了一般智力和“大五”人格特质的影响后，结果仍然存在。更重要的是，右DMPFC的fALFF在坚毅与学业成绩之间起着中介作用。总的来说，这些发现揭示了区域fALFF作为砂砾的神经基础，并强调了正确的DMPFC作为砂砾和学习成绩之间的神经联系。
Abstract As a personality trait, grit involves the tendency to strive to achieve long-term goals with continual passion and perseverance and plays an extremely crucial role in personal achievement. However, the neural mechanisms of grit remain largely unknown. In this study, we aimed to explore the association between grit and the fractional amplitude of low-frequency fluctuations (fALFF) in 217 healthy adolescent students using resting-state functional magnetic resonance imaging (RS-fMRI). We found that an individual’s grit was negatively related to the regional fALFF in the right dorsomedial prefrontal cortex (DMPFC), which is involved in self-regulation, planning, goal setting and maintenance, and counterfactual thinking for reflecting on past failures. The results persisted even after the effects of general intelligence and the ‘big five’ personality traits were adjusted for. More importantly, the fALFF of the right DMPFC played a mediating role in the association between grit and academic performance. Overall, these findings reveal regional fALFF as a neural basis of grit and highlight the right DMPFC as a neural link between grit and academic performance.