Quantitative Assessment and Interpretation of Vaginal Conditions.
Quantitative Assessment and Interpretation of Vaginal Conditions.
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DOI：
10.1016/j.esxm.2017.08.002
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发表时间：
2018-03
期刊：
影响因子：
2.6
通讯作者：
Sarvazyan N
中科院分区：
文献类型：
--
作者：
Egorov V;Murphy M;Lucente V;van Raalte H;Ephrain S;Bhatia N;Sarvazyan N
很少有方法可以从生物力学和功能的角度对阴道状况进行定量和可重复的评估。目的：发展一种新的阴道定量生物力学表征方法。阴道触觉成像（VTI）允许沿着阴道前、后、侧壁的整个长度对软组织和功能进行生物力学评估。这可以在休息时进行，阴道变形，盆腔肌肉收缩。我们分析了一项观察性病例对照临床研究中42名骨盆底支撑正常的受试者的数据。平均年龄52岁（范围26-90岁）。我们引入了8个VTI参数来表征阴道状况：(i)最大插入阻力（牛顿），（ii）插入功（毫焦耳），（iii）最大应力应变比（弹性；千帕斯卡/毫米），（iv）最大静止压力（千帕斯卡），(v)静止前后力（牛顿），（vi）静止左右力（牛顿），（vii）肌肉收缩时最大压力（千帕斯卡），（viii）肌肉收缩力（牛顿）。我们观察到这些参数与受试者年龄有低到中等程度的相关性，与受试者体重无相关性。8个参数中有6个参数的P值小于。2个被试子样本按年龄划分（≤52 vs >52岁）为05，即6个VTI参数随年龄变化。VTI允许对阴道状况进行生物力学和功能表征，可用于(i)了解“正常”阴道状况，（ii）对正常情况的偏差进行量化，（iii）个性化治疗（射频、激光或整形手术），以及（iv）评估应用治疗结果。Egorov V, Murphy M, Lucente V，等。阴道状况的定量评估和解释。性医学2018；6:39-48。
Few means exist to provide quantitative and reproducible assessment of vaginal conditions from biomechanical and functional standpoints. To develop a new approach for quantitative biomechanical characterization of the vagina. Vaginal tactile imaging (VTI) allows biomechanical assessment of soft tissue and function along the entire length of the anterior, posterior, and lateral vaginal walls. This can be done at rest, with applied vaginal deformation, and with pelvic muscle contraction. Data were analyzed for 42 subjects with normal pelvic floor support from an observational case-controlled clinical study. The average age was 52 years (range = 26–90 years). We introduced 8 VTI parameters to characterize vaginal conditions: (i) maximum resistance force to insertion (newtons), (ii) insertion work (millijoules), (iii) maximum stress-to-strain ratio (elasticity; kilopascals per millimeter), (iv) maximum pressure at rest (kilopascals), (v) anterior-posterior force at rest (newtons), (vi) left-right force at rest (newtons), (vii) maximum pressure at muscle contraction (kilopascals), and (viii) muscle contraction force (newtons). We observed low to moderate correlation of these parameters with subject age and no correlation with subject weight. 6 of 8 parameters demonstrated a P value less than .05 for 2 subject subsamples divided by age (≤52 vs >52 years), which means 6 VTI parameters change with age. VTI allows biomechanical and functional characterization of the vaginal conditions that can be used for (i) understanding “normal” vaginal conditions, (ii) quantification of the deviation from normality, (iii) personalized treatment (radiofrequency, laser, or plastic surgery), and (iv) assessment of the applied treatment outcome. Egorov V, Murphy M, Lucente V, et al. Quantitative Assessment and Interpretation of Vaginal Conditions. Sex Med 2018;6:39–48.
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影响因子：
1.8
作者：
Slieker-ten Hove, Marijke C. Ph.;Pool-Goudzwaard, Annelies L.;Vierhout, Mark E.
通讯作者：
Vierhout, Mark E.
影响因子：
--
作者：
Murad-Regadas, Sthela Maria;Regadas, Francisco Sergio P;Dealcanfreitas, Íris Daiana
通讯作者：
Dealcanfreitas, Íris Daiana
影响因子：
10.6
作者：
Egorov V;Sarvazyan AP
通讯作者：
Sarvazyan AP
影响因子：
1.8
作者：
Egorov, Vladimir;van Raalte, Heather;Lucente, Vincent
通讯作者：
Lucente, Vincent
DOI：
10.1109/tbme.2010.2045757
发表时间：
2010-07
期刊：
IEEE transactions on bio-medical engineering
影响因子：
--
作者：
Egorov V;van Raalte H;Sarvazyan AP
通讯作者：
Sarvazyan AP