Measurements of Solubilities of Two Amino Acids in Water and Prediction by the UNIFAC Model
Measurements of Solubilities of Two Amino Acids in Water and Prediction by the UNIFAC Model
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DOI：
10.1021/bp960016m
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发表时间：
1996
影响因子：
2.9
通讯作者：
H. Kuramochi;H. Noritomi;Daisuke Hoshino;Kunio Nagahama
中科院分区：
文献类型：
--
作者：
H. Kuramochi;H. Noritomi;Daisuke Hoshino;Kunio Nagahama
The solubility of an amino acid in an aqueous solution containing another amino acid was measured at 298 K. The measured amino acid pairs were dl‐alanine/dl‐serine and dl‐alanine/dl‐valine. The invariant eutectic compositions of these pairs of amino acids were also determined. In addition, a prediction model of solubility for such a system was developed on the basis of solid−liquid equilibria. To represent more accurately the activity coefficient of amino acids and homopeptides by Larsen's UNIFAC model, new assignments of UNIFAC groups were proposed and their interaction parameters were determined from experimental osmotic coefficient data. Finally, the prediction of solubilities of mixed solid amino acids was made and the results were compared with experimental data.
