Multi-Functionalization of Solid Support via Zn(II)-Mediated Chirality-Directed Self-Assembly
Multi-Functionalization of Solid Support via Zn(II)-Mediated Chirality-Directed Self-Assembly
复制标题
通过 Zn(II) 介导的手性定向自组装实现固体载体的多功能化
DOI：
10.1055/a-2106-9071
复制
发表时间：
2023
影响因子：
--
通讯作者：
Moteki, Shin A.
中科院分区：
文献类型：
--
作者：
Overshiner, Max S.;Tian, Shuyuan;Morrow, Kegan B.;Wendt, Jailyn R.;Zhou, John;Briggs, Hannah M.;Márquez, Gerardo B.;Kilway, Kathleen V.;Moteki, Shin A.
建立实现程序化自组装的策略是制造具有功能性杂化结构的材料的关键。在这项工作中，我们介绍了一种使用手性定向自组装概念实现多组分自组装的稳健方法。当在Zn（Oac）2的存在下混合手性BOX配体的对映异构体的组合时，可以选择性地产生异手性Zn（II）亚甲基双（恶唑啉）（BOX）络合物的特定组合。与非共价键不同，所得的Zn（II）BOX络合物是高度稳定的，并且在升高的温度下保持完整，但可以在温和条件下使用EDTA可逆地分解。这种方法可以很容易地应用于多功能化的各种固体支持物，使一锅生成的多功能的混合结构。
Establishing a strategy for realizing programmed self-assembly is critical in manufacturing materials with functional hybrid structures. In this work, we introduce a robust methodology for enabling multi-component self-assembly using the concept of chirality-directed self-assembly. A specific combination of heterochiral Zn(II) methylene bis(oxazoline) (BOX) complexes can be selectively generated when combinations of enantiomers of chiral BOX ligands are mixed in the presence of Zn(Oac)2. The resulting Zn(II) BOX complexes, unlike non-covalent bonds, are highly stable and stay intact at elevated temperatures, yet can be reversibly disintegrated under mild conditions using EDTA. This approach can be easily applied to multi-functionalize various solid supports enabling the one-pot generation of multi-functional hybrid structures.