Scanning-aperture trapping and manipulation of single charged nanoparticles
Scanning-aperture trapping and manipulation of single charged nanoparticles
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DOI：
10.1038/ncomms4380
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发表时间：
2014-03-01
影响因子：
16.6
通讯作者：
Sandoghdar, Vahid
中科院分区：
文献类型：
--
作者：
Kim, Ji Tae;Spindler, Susann;Sandoghdar, Vahid
虽然小物体的捕获和操纵已经引起了一系列应用的兴趣，并且已经设计了许多聪明的技术，但仍然需要新的方法来处理不同的材料和几何形状。在这里，我们报告的静电陷阱，在水性介质中创建的纳米移液管的孔径和玻璃基板之间，而不需要外部电位。经过一个彻底的表征的捕获条件，我们表明，我们可以取代或释放一个粒子的意愿。此外，我们证明了捕获和操纵的纳米粒子和脂质囊泡连接到脂质双层，铺平了道路，与生物膜相关的力和扩散的控制研究。我们期望该技术在其他领域也能找到有趣的应用，如optonanofluidics和plasmonics。
Although trapping and manipulation of small objects have been of interest for a range of applications and many clever techniques have been devised, new methods are still in great demand for handling different materials and geometries. Here, we report on an electrostatic trap that is created in an aqueous medium between the aperture of a nanopipette and a glass substrate without the need for external potentials. After a thorough characterization of the trapping conditions, we show that we can displace or release a particle at will. Furthermore, we demonstrate trapping and manipulation of nanoparticles and lipid vesicles attached to lipid bilayers, paving the way for controlled studies of forces and diffusion associated with biological membranes. We expect the technique to find interesting applications also in other areas such as optonanofluidics and plasmonics.