COMPUTERIZED RADIOGRAPHIC ANALYSIS OF OSTEOPOROSIS - PRELIMINARY EVALUATION
COMPUTERIZED RADIOGRAPHIC ANALYSIS OF OSTEOPOROSIS - PRELIMINARY EVALUATION
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DOI：
10.1148/radiology.186.2.8421753
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发表时间：
1993-02-01
期刊：
影响因子：
19.7
通讯作者：
DIXON, LB
中科院分区：
文献类型：
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作者：
CALIGIURI, P;GIGER, ML;DIXON, LB
骨量测量对于确定骨折风险以及跟踪接受骨质疏松症治疗的患者的病程非常重要。骨密度测定 (BMD) 是骨折风险的良好预测指标，但有骨折风险的个体和无骨折风险的个体之间的 BMD 测量值存在相当大的重叠。在这项研究中，对传统脊柱射线照片上的小梁模式进行计算机化纹理分析，用于评估骨结构作为骨折风险的决定因素。对 43 名个体的标准腰椎 X 光片进行了分析，并与双光子吸收法获得的 BMD 测量值进行了比较。在区分脊柱其他部位骨折的患者与无骨折的患者方面，该方法比 BMD 更有效。这些初步结果表明，这种骨结构分析方法与 BMD 相结合，可能会产生更灵敏、更特异的骨质疏松症和骨折风险预测指标。
Measurement of bone mass is important in determining the risk for fracture and in following the course of patients undergoing therapy for osteoporosis. Bone mineral densitometry (BMD) is a good predictor of fracture risk, but there is considerable overlap in BMD measurements between individuals with fracture risk and those without. In this study, computerized texture analysis of the trabecular pattern on conventional spine radiographs was used to evaluate bone structure as a determinant of fracture risk. Standard lumbar spine radiographs of 43 individuals were analyzed and compared with BMD measurements obtained with dual-photon absorptiometry. This method was more effective than BMD in differentiation of patients with fractures elsewhere in the spine from those with no fracture. These preliminary results suggest that this method of bone structure analysis, combined with BMD, may lead to a more sensitive and specific predictor of osteoporosis and risk of fracture.