Advances in coronary MRA from vessel wall to whole heart imaging.
Advances in coronary MRA from vessel wall to whole heart imaging.
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DOI：
10.2463/mrms.6.157
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发表时间：
2007-01-01
期刊：
影响因子：
--
通讯作者：
Nehrke, Kay
中科院分区：
文献类型：
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作者：
Stehning, Christian;Boernert, Peter;Nehrke, Kay
自问世以来，磁共振(MR)成像技术和方法经历了不断的发展，并发现了许多实际的临床应用。心脏MR成像是MR较为复杂的应用之一，因为其固有的流动和运动的存在以及特定的解剖结构。在不同类型的心脏MR成像中，冠状动脉MR血管成像(MRA)对规划、空间分辨率、高信噪比(SNR)以及精确的心脏和呼吸运动校正提出了特别高的要求。然而，硬件、MR序列和运动检测技术的最新进展使得在临床可接受的扫描时间内执行冠状动脉MRA成为可能，其包括整个心脏的体积采集以及在亚毫米尺度上的血管壁成像。我们从技术角度讨论了导致冠状动脉磁共振成像现状的一些里程碑，并概述了将进一步推进冠状动脉磁共振成像的最新发展。我们讨论了计划程序、对比剂准备机制和MR序列、运动校正、高分辨率冠状动脉和血管壁成像以及快速容积扫描技术。虽然磁共振成像在同时提供速度、分辨率和高信噪比方面有一定的局限性，但它仍然提供了一种专门的扫描程序，解决了缺血性心脏病诊断中最相关的临床问题。
Since its introduction, magnetic resonance (MR) imaging has undergone continued technical and methodological development and found numerous practical clinical applications. Cardiac MR imaging is one of the more sophisticated applications of MR, owing to the inherent presence of flow and motion and specific anatomy. Among the different categories of cardiac MR imaging, coronary MR angiography (MRA) places particularly high demands on planning, spatial resolution, high signal-to-noise ratio (SNR), and precise cardiac and respiratory motion correction. However, recent advances in hardware, MR sequences, and motion detection techniques have made it possible to perform coronary MRA that includes volumetric acquisition of the entire heart as well as imaging of the vessel walls on a submillimeter scale within a clinically acceptable scan time. We discuss from a technical perspective some of the milestones leading to the current state of coronary MR imaging and outline recent developments that will further advance coronary MR imaging. We discuss planning procedure, contrast preparation mechanisms and MR sequences, motion correction, high-resolution coronary artery and vessel wall imaging, and fast volumetric scanning techniques. Although MR imaging has certain limitations in providing simultaneous speed, resolution, and high SNR, it nonetheless offers a dedicated scanning procedure that addresses most clinically relevant questions in the diagnosis of ischemic heart disease.