Use of electron beam for the production of hydrogel dressings
Use of electron beam for the production of hydrogel dressings
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DOI：
10.1016/j.radphyschem.2007.05.016
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发表时间：
2008-02-01
影响因子：
2.9
通讯作者：
Dada, H.
中科院分区：
文献类型：
--
作者：
Ajji, Z.;Mirjaliji, G.;Dada, H.
电子束辐照技术已被用于制备水凝胶伤口敷料。敷料的成分基于聚乙烯吡咯烷酮（PVP）、聚乙二醇（PEG）和琼脂。增加辐照剂量导致凝胶分数增加;这种增加是由于交联密度增加。凝胶分数%随着PEG浓度的增加而降低。最大溶胀率随辐照剂量的增加而减小，但随PEG浓度的增加而增大。该关系可用于改变凝胶性质，如凝胶分数%和水凝胶的最大溶胀。所制备的敷料可以被认为是对微生物的良好屏障。(c)2007爱思唯尔有限公司版权所有。
The electron beam irradiation technique has been utilized to prepare hydrogel wound dressings. The composition of the dressings is based on polyvinylpyrrolidone (PVP), poly(ethylene glycol) (PEG), and agar. Increasing the irradiation dose leads to an increase in the gel fraction; this increase is due to increased crosslink density. The gel fraction% decreases as the PEG concentration increases. The maximum swelling% decreases with increasing the irradiation dose, but increases with increasing the PEG concentration. This relationship can be utilized to modify the gel properties as gel fraction% and maximum swelling of the hydrogel. The prepared dressings could be considered as a good barrier against microbes. (c) 2007 Elsevier Ltd. All rights reserved.