DEVELOPMENT OF THE HEART
DEVELOPMENT OF THE HEART
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心脏的发育
DOI：
10.1136/bmj.2.5163.1387
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发表时间：
1959
影响因子：
--
通讯作者：
G. Graham
中科院分区：
文献类型：
--
作者：
G. Graham
心脏正常发育和病理改变。克劳斯·戈特勒写的。(pp.123；插图。DM。33.)斯图加特：Georg Thieme Verlag。1958年。近年来，在先天性心脏病的诊断和外科治疗方面的进展使人类心脏的正常和异常发育成为一个比平时更感兴趣的课题。基尔大学病理研究所的K.Goerttler多年来一直试图将各种事实和假设纳入一个一般理论，用于解释先天性心脏病病变的发展。他特别强调了血液动力学因素在其发生中的影响。这本专著总结了他的工作和观点，同时批判性地考虑了其他人所做的工作。这本书分为两个主要部分。总论部分阐述了心脏正常发育和异常发育的基本原理。正常的纵向生长、环状和内部结构被认为依赖于在关键时期原始心管某些部分的特别高的代谢活动。流入和流出部分的划分被认为是由血液动力学决定的，隔膜是次要现象。所有先天性心脏缺陷都被认为是心脏某些部位生长受阻的结果，这些部位在特定时间是代谢最活跃的，因此特别容易受到(未指明的)内源性或外源性致畸剂的影响。许多血管异常被认为是“依赖于”一个或多个原发心脏缺陷。第二部分详细讨论心脏生长发育的不同阶段的畸形学(其中四个阶段是有区别的)。每个阶段及其相关的异常都是单独分析的，通常辅以一到两个尸检标本的仔细描述。几页的结论和一个总结结束了正文。有一个广泛的参考文献清单，但它绝不是完整的。因此，阿瑟·基思爵士的工作和观点没有被提及。总而言之，有一种轻微的倾向，就是把已经被广泛接受的东西作为新的东西呈现--至少在英美圈子里是这样。与图表的清晰和巧妙形成鲜明对比的是，图表在说明复杂的三维旋转变化时最为成功，而文本往往过于冗长和曲折。尤其令人恼火的是，在高度复杂的句子中加入解释性或批判性评论--有时听起来很随意，但有时却带来了对作者论点非常重要的材料--作为子句。那些对这个主题感兴趣的人会发现这是一本有价值和有价值的书，但这本书需要很好的德语知识。产品质量好，价格合理。杰拉尔德·R·格雷厄姆。
DEVELOPMENT OF THE HEART Normale und Pathologische Entwicklung des Menschlichen Herzens. By Klaus Goerttler. (Pp. 123; illustrated. DM. 33.) Stuttgart: Georg Thieme Verlag. 1958. Recent advances in the diagnosis and surgical treatment of congenital heart disease have made the normal and abnormal development of the human heart a subject of more than usual interest. K. Goerttler, of the University Institute of Pathology at Kiel, has over a number of years tried to fit the various facts and hypotheses into a general theory which would serve to explain the development of congenital heart lesions. In particular, he has stressed the influence of haemodynamic factors in their genesis. This monograph summarizes his work and views, while taking critical account of the work done by others. The book is divided into two main sections. The general part describes the basic principles in the normal and abnormal development of the heart. Normal longitudinal growth, looping, and internal structuring are taken to depend on especially high metabolic activity in certain parts of the primitive cardiac tube at critical periods. The division into inflow and outflow portions is thought to be haemodynamically determined, with septation a secondary phenomenon. All congenital cardiac defects are considered to be the result of differential growth arrests of those parts of the heart which, at a given time, are metabolically most active and thus particularly vulnerable to (unspecified) endogenous or exogenous teratogenic agents. Many of the vascular anomalies are thought of as " dependent" upon the primary cardiac defect or defects. The second part treats in detail of the teratology of the different phases (of which four are distinguished) in the growth and development of the heart. Each phase and its associated anomalies are analysed separately, usually aided by a careful description of one or two necropsy specimens. A few pages of conclusions and a summary end the text. There is an extensive list of references, but it is by no means complete. Thus Sir Arthur Keith's work and views find no mention. Altogether there is the slight tendency to present as new what has already found wide acceptance -at least in Anglo-American circles. In contrast to the clarity and ingeniousness of the diagrams, which are most successful when illustrating the complex three-dimensional rotational changes, the text is often tryingly verbose and tortuous. Especially annoying is the inclusion of explanatory or critical comments-sometimes sounding off-hand, but sometimes bringing material of great importance to the author's argument-as sub-clauses in highly involved sentences. Those interested in the subject will find this a worthwhile and rewarding book, but one which requires a good knowledge of German. The production is good and the price reasonable. GERALD R. GRAHAM.