Incidence and Clinical Characteristics of Post LASIK Ectasia: A Review of over 30,000 LASIK Cases

Incidence and Clinical Characteristics of Post LASIK Ectasia: A Review of over 30,000 LASIK Cases
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DOI:
10.1080/08820538.2018.1539183
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发表时间:
2018-11-17
影响因子:
1.7
通讯作者:
Patel, Sudi
Patel, Sudi
中科院分区:
医学4区
文献类型:
--
作者:
Bohac, Maja;Koncarevic, Mateja;Patel, Sudi

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目的:报道准分子激光原位角膜磨镶术(LASIK)术后角膜扩张症的发生率。方法:对2007年8月至2015年8月LASIK术后30,167只眼(16,732例)患者进行了回顾性病例回顾。术后随访2~8年。术后2年行体层摄影术。在确定了扩张症的病例后,检查了这些患者的图表,以确定可能导致他们发生扩张症的任何共同因素。结果:7名患者的10只眼发生了LASIK术后扩张症。治疗近视和近视散光8只眼,混合散光2只眼。无远视LASIK术后扩张者。10例角膜扩张症患者均采用Moria M2机械式微角膜刀制作角膜瓣(平均厚度118.15±12.88µm),并用准分子激光矫正屈光不正。回顾,最普遍的危险因素是角膜薄(3例(40%),组织厚度改变百分比=40%(20%)和低残留基质床(
Purpose: To report the incidence of postoperative ectasia after laser in situ keratomileusis (LASIK). Methods: A retrospective case review of 30,167 eyes (16,732 patients) was conducted following LASIK between August 2007 and August 2015. The follow-up was between 2 and 8 years. Tomography was performed after 2 years postop. After identifying cases of ectasia, the charts of these patients were examined to identify any common factors that may have predisposed them to develop ectasia. Results: Ten eyes of seven patients developed post-LASIK ectasia. Eight eyes had been treated for myopia and myopic astigmatism, two eyes for mixed astigmatism. There were no cases of ectasia after LASIK for hyperopia. All 10 cases of ectasia had a flap that was created using the Moria M2 mechanical microkeratome (average flap thickness 118.15 +/- 12.88 mu m) and refractive error corrected using the Wavelight Allegretto excimer laser. Retrospectively, most prevalent risk factors were thin cornea ( 3 (40% of cases), percent tissue thickness alteration >= 40% (20% of cases) and low residual stromal bed (