Costimulation blockade-a double-edged sword?

Costimulation blockade-a double-edged sword?
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共刺激封锁——一把双刃剑?

DOI:
10.1111/j.1600-6143.2012.04185.x
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发表时间:
2012
期刊:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
影响因子:
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通讯作者:
Maltzman,JS
Maltzman,JS
中科院分区:
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文献类型:
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作者:
Maltzman,JS

文献摘要

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The author describes the findings of Riella et al (see April issue) and Charbonnier et al (see page 2313) that CTLA4Ig worsens outcomes in regulatory T cell–dependent models of transplantation and discusses how these findings may impact future research and clinical use of related drugs.