Syntheses of defined sulfated oligohyaluronans reveal structural effects, diversity and thermodynamics of GAG–protein binding
Syntheses of defined sulfated oligohyaluronans reveal structural effects, diversity and thermodynamics of GAG–protein binding
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DOI：
10.1039/c8sc03649g
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发表时间：
2018-11
期刊：
影响因子：
8.4
通讯作者：
Sebastian Köhling;Joanna Blaszkiewicz;Gloria Ruiz-Gómez;M. I. Fernández-Bachiller;Katharina Lemmnitzer;N. Panitz;Annette G. Beck‐Sickinger;J. Schiller;M. T. Pisabarro;J. Rademann
中科院分区：
文献类型：
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作者：
Sebastian Köhling;Joanna Blaszkiewicz;Gloria Ruiz-Gómez;M. I. Fernández-Bachiller;Katharina Lemmnitzer;N. Panitz;Annette G. Beck‐Sickinger;J. Schiller;M. T. Pisabarro;J. Rademann
GAG对细胞外调节蛋白的高结合亲和力受识别多样性、硫酸化模式、长度和异头官能化控制。
High binding affinities of GAG toward extracellular regulatory proteins are governed by recognition diversity, sulfation pattern, length, and anomeric functionalization.