Immunologic Characterization and Quantification of Haemoglobin A1c
Immunologic Characterization and Quantification of Haemoglobin A1c
复制标题
A1c 血红蛋白的免疫学表征和定量
DOI：
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发表时间：
1978
影响因子：
6.5
通讯作者：
A. Cerami
中科院分区：
文献类型：
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作者：
J. Javid;Penelope K. Pettis;Ronald J. Koenig;A. Cerami
羊抗血清开发的人糖化血红蛋白，血红蛋白A1c，区分这部分的主要成分血红蛋白A0。与Hb A1a和Hb A1b以及小鼠和犬溶血产物中的类似糖血红蛋白观察到部分交叉反应性。血红蛋白与这种特异性抗血清的反应性通过糖配体的酮基的还原而消除。
Sheep antiserum developed against the human glycohaemoglobin, Hb A1c, distinguishes this fraction from the major component Hb A0. Partial cross reactivity is observed with Hb A1a and Hb A1b, as well as with analogous glycohaemoglobins from mouse and dog haemolysates. The reactivity of the haemoglobins with this specific antiserum is abolished by the reduction of the keto group of the sugar ligand.