MANAGEMENT OF CANCER PAIN - PHARMACOLOGY AND PRINCIPLES OF MANAGEMENT
MANAGEMENT OF CANCER PAIN - PHARMACOLOGY AND PRINCIPLES OF MANAGEMENT
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DOI：
10.1002/1097-0142(19890601)63:11
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发表时间：
1989-06-01
期刊：
影响因子：
6.2
通讯作者：
INTURRISI, CE
中科院分区：
文献类型：
--
作者：
INTURRISI, CE
绝大多数癌症患者的疼痛可以通过使用止痛药来控制。药代动力学和临床研究为癌痛的药物治疗指南提供了基础。这些指南的基本概念是个体化治疗，其目标是最大限度地缓解疼痛和最小化药物不良反应。本文介绍了这些指南，并讨论了常用的止痛药在治疗癌症疼痛的药理学特性和不良反应。还审查了避免和治疗镇痛药的不良反应的方法。
The pain of the vast majority of patients with cancer can be controlled with the use of analgesic drugs. Pharmacokinetic and clinical studies have provided the basis for guidelines for the pharmacologic management of cancer pain. The fundamental concept underlying these guidelines is individualization of therapy, which has as its goal the maximization of pain relief and the minimization of adverse drug effects. This article presents these guidelines and discusses the pharmacologic properties and adverse effects of analgesic drugs commonly used in the treatment of cancer pain. Also reviewed are methods for avoiding and treating the adverse effects of analgesics.