A self-healable fluorescence active hydrogel based on ionic block copolymers prepared via ring opening polymerization and xanthate mediated RAFT polymerization
A self-healable fluorescence active hydrogel based on ionic block copolymers prepared via ring opening polymerization and xanthate mediated RAFT polymerization
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DOI：
10.1039/c7py01883e
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发表时间：
2018-03-14
影响因子：
4.6
通讯作者：
Singha, Nikhil K.
中科院分区：
文献类型：
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作者：
Banerjee, Sovan Lal;Hoskins, Richard;Singha, Nikhil K.
在这项工作中，我们报告了一种简单的方法，通过掺入荧光响应离子嵌段共聚物（bcp）来制备荧光活性自愈水凝胶。通过开环聚合（ROP）和黄药介导的可逆加成-破碎链转移（RAFT）聚合，制备了离子嵌段共聚物。本文用黄药对聚己内酯（PCL）进行改性，制备了一种基于PCL的宏观raft剂，然后利用PCL制备了阳离子型聚2-（甲基丙烯氧基）乙基三甲基氯化铵（PCL-b- pmtac）和阴离子型聚4-乙烯基苯磺酸钠（PCL-b- pss）嵌段共聚物。在嵌段形成过程中，阳离子段随机与微量的荧光素o -丙烯酸酯（FA）（受体）共聚，阴离子段随机与微量的9-甲基丙烯酸甲酯（AMMA）（供体）共聚，使两个片段都具有荧光。嵌段共聚物在DMF：水混合物（1:4体积比）中形成胶束。通过福斯特共振能量转移（FRET）和zeta电位测量来监测两种bcp的离子相互作用。将带相反电荷的bcp加入到基于聚丙烯酰胺（PAAm）的水凝胶中，该水凝胶具有自修复行为，并且具有高荧光性。
In this work we report a facile method to prepare a fluorescence active self-healable hydrogel via incorporation of fluorescence responsive ionic block copolymers (BCPs). Ionic block copolymers were prepared via a combined effect of ring opening polymerization (ROP) of epsilon-caprolactone and xanthate mediated reversible addition-fragmentation chain transfer (RAFT) polymerization. Here polycaprolactone (PCL) was modified with xanthate to prepare a PCL based macro-RAFT agent and then it was utilized to prepare block copolymers with cationic poly(2-(methacryloyloxy) ethyltrimethyl ammonium chloride) (PCL-b-PMTAC) and anionic poly(sodium 4-vinylbenzenesulfonate) (PCL-b-PSS). During the block formation, the cationic segments were randomly copolymerized with a trace amount of fluorescein O-acrylate (FA) (acceptor) whereas the anionic segments were randomly copolymerized with a trace amount of 9-anthryl methylmethacrylate (AMMA) (donor) to make both the segments fluorescent. The block copolymers form micelles in a DMF : water mixture (1 : 4 volume ratio). The ionic interaction of two BCPs was monitored via Forster resonance energy transfer (FRET) and zeta potential measurements. The oppositely charged BCPs were incorporated into a polyacrylamide (PAAm) based hydrogel that demonstrated self-healing behavior and is also highly fluorescent.