Poliomyelitis Component in Quadruple Antigen: Controlled Clinical Study of Enhanced Response of Children
Poliomyelitis Component in Quadruple Antigen: Controlled Clinical Study of Enhanced Response of Children
复制标题
四联抗原中的脊髓灰质炎成分：儿童增强反应的对照临床研究
DOI：
10.1001/jama.1960.03030090022005
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发表时间：
1960
期刊：
影响因子：
--
通讯作者：
Francis P. Staffieri
中科院分区：
文献类型：
--
作者：
D. Bordt;J. W. Whalen;P. A. Boyer;A. R. Pursell;Francis P. Staffieri
The immunologic effects of quadruple diphtheria, tetanus, pertussis, poliomyelitis aluminum phosphate adsorbed vaccine were compared with triple diphtheria, tetanus, and pertussis aluminum phosphate adsorbed vaccine alone and poliomyelitis vaccine alone. A total of 192 children who had not been previously immunized with the respective antigens were studied. The poliomyelitis antibody responses were significantly greater with quadruple vaccine than with poliomyelitis vaccine alone. The diphtheria antibody responses were greater with quadruple vaccine than with triple vaccine. The antibody responses for tetanus and pertussis were essentially the same for both vaccines.
