Deficits in recall following partial and complete commissurotomy.
Deficits in recall following partial and complete commissurotomy.
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DOI：
10.1093/cercor/1.6.492
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发表时间：
1991-11
期刊：
影响因子：
3.7
通讯作者：
E. Phelps;W. Hirst;M. Gazzaniga
中科院分区：
文献类型：
--
作者：
E. Phelps;W. Hirst;M. Gazzaniga
在文献中已经报道了受损的（Zaidel和Sperry，1974）和完整的（LeDoux等人，1977）胼胝体切开术后的记忆性能。在本文中，对接受部分或完全胼胝体切开术的患者进行记忆检查，以确定（1）胼胝体切开术后是否存在记忆缺陷，（2）某些类型的胼胝体切开术是否更可能导致缺陷（即，前部与后部），以及（3）是否存在整体记忆缺陷或是否某些记忆功能比其他功能受到更多的影响。接受胼胝体部分或完整切片的患者在术前和术后进行标准化记忆测试和回忆与识别测试。此外，两名患者完全胼胝体切开术和匹配的对照组进行了言语回忆和识别测试。在视觉和语言回忆的赤字被发现在后节的患者，但不是那些接受前节。任何患者的言语识别测试均未发现损害。后胼胝体切片通常包括海马连合和其他海马连接，而前切片不包括。鉴于海马体的重要性（米尔纳，1970）以及回忆记忆和再认记忆在正常记忆功能中的差异（Bransford和约翰逊，1972），人们提出了几种假设来解释为什么会出现这些结果。
There have been reports in the literature of both impaired (Zaidel and Sperry, 1974) and intact (LeDoux et al., 1977) memory performance following callosotomy. In the present article, memory is examined in patients who received either partial or complete callosotomy in an effort to determine (1) if there is a memory deficit following callosotomy, (2) if certain types of callosotomy are more likely to lead to a deficit (i.e., anterior vs posterior), and (3) if there is a global memory deficit or if some mnemonic functions are affected more than others. Patients receiving either partial or complete section of the corpus callosum were examined pre- and postoperatively on standardized memory tests and tests of recall and recognition. In addition, two patients with complete callosotomy and matched control subjects were given tests of verbal recall and recognition. A deficit in both visual and verbal recall was found in patients with posterior section, but not those receiving anterior section. No impairment was found on tests of verbal recognition for any patients. Posterior callosal section generally includes the hippocampal commissure and other hippocampal connections, while anterior sectioning does not. Given the known importance of the hippocampus (Milner, 1970) and the differences between recall and recognition memory (Bransford and Johnson, 1972) in normal memory functioning, several hypotheses are proposed as to why these results might be expected.