Diaschisis with Cerebral Infarction
Diaschisis with Cerebral Infarction
复制标题
脑梗死伴神经联系联系不全
DOI：
10.1161/01.str.8.6.684
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发表时间：
1977
期刊：
影响因子：
8.3
通讯作者：
J. Greenberg
中科院分区：
文献类型：
--
作者：
R. Slater;M. Reivich;H. Goldberg;R. Banka;J. Greenberg
费城综合医院收治的 15 名急性中风患者通过 133Xenon 吸入法重复测量脑血流量。在 12 名患者梗死后的第一周内，观察到两个半球的脑血流量进行性下降。这种下降的部分原因可能是自动调节功能丧失，但与意识水平、临床状态或 Pco2 无关。非缺血半球中血流的逐渐下降表明一个过程比神经元轴突传入神经元的简单破坏更为复杂，如术语神经联系联系所暗示的那样。非缺血半球的血流变化可能是由神经元刺激减少、自动调节丧失、血管活性物质释放、脑水肿和其他因素改变的直接影响共同引起的。
Fifteen patients admitted to Philadelphia General Hospital with acute strokes had repeated measurements of cerebral blood flow measured by the 133Xenon inhalation method. A progressive decline in cerebral blood flow in both hemispheres was observed during the first week after infarction in twelve of these patients. This decline could be partially explained by loss of autoregulation, but could not be correlated with level of consciousness, clinical status or Pco2. This progressive decline in flow in the nonischemic hemisphere indicates a process more complex than a simple destruction of axonal afferants to neurons as implied by the term diaschisis. The flow changes in the non-ischemic hemisphere are likely caused by a combination of the immediate effects of decreased neuronal stimulation modified by loss of autoregulation, release of vasoactive substances, cerebral edema, and other factors.