CHARACTERIZATION OF RESPIRATORY-RELATED ACTIVITY OF THE FACIAL-NERVE
CHARACTERIZATION OF RESPIRATORY-RELATED ACTIVITY OF THE FACIAL-NERVE
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DOI：
10.1016/0034-5687(88)90065-5
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发表时间：
1988-08-01
期刊：
影响因子：
--
通讯作者：
STJOHN, WM
中科院分区：
文献类型：
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作者：
HWANG, JC;CHIEN, CT;STJOHN, WM
记录了去大脑和瘫痪猫的面部神经、舌下神经和膈神经的活动。这些动物使用伺服呼吸器进行通气，该呼吸器在膈活动的同时产生肺部膨胀。高碳酸血症或缺氧时吸气峰峰值、舌下肌和面部活动增加。当肺膨胀被阻止时，舌下和面部活动比膈活动增加更多。对抑制肺部充气的反应与迷走神经切断术后的反应不同。这些差异在呼气面部和舌下活动以及高碳酸血症和缺氧引起的面部活动变化中观察到。给予戊巴比妥或过度通气以治疗低碳酸血症，对舌下活动的抑制比对面部活动的抑制更大；后者比膈活动下降得更多。结果支持以下假设：与球脊髓膈系统的影响相比，脑干网状结构和肺牵张感受器的影响在支配上气道肌肉的运动神经元上的分布存在差异。讨论了通气活动受强直以及肺受体的阶段性放电影响的概念。
Activities of the facial, hypoglossal and phrenic nerves were recorded in decerebrate and paralyzed cats. These animals were ventilated with a servo-respirator which produced lung inflations in parallel with phrenic activity. Peak inspiratory phrenic, hypoglossal and facial activities increased in hypercapnia or hypoxia. When pulmonary inflation was prevented, hypoglossal and facial activities increased more than phrenic. Responses to withholding lung inflation differed from those following vagotomy. These differences were observed in expiratory facial and hypoglossal activities and in hypercapnia- and hypoxia-induced changes in facial activity. Administration of pentobarbital or hyperventilation to hypocapnia caused greater suppressions of hypoglossal than facial activity; the latter declined more than phrenic activity. The results support the hypothesis that influences from the brainstem reticular formation and from pulmonary stretch receptors are differentially distributed to motoneurons innervating upper airway muscles compard to those of the bulbospinal-phrenic system. The concept that ventilatory activity is influenced by tonic, as well as phasic discharge of pulmonary receptors is discussed.