Image analysis in patients with cancer studied with a combined PET and CT scanner
Image analysis in patients with cancer studied with a combined PET and CT scanner
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DOI：
10.1097/00003072-200011000-00010
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发表时间：
2000-11-01
影响因子：
10.6
通讯作者：
Townsend, DW
中科院分区：
文献类型：
--
作者：
Charron, M;Beyer, T;Townsend, DW
目的：比较结合全身PET和CT图像的不同cancer with PET images alone.Materials and Methods：32例已知或可能的癌症患者进行了检查，使用正电子发射断层扫描（PET）和计算机断层扫描（CT）扫描仪。所有数据均使用同一组合扫描仪采集。在注射F-18氟脱氧葡萄糖（FDG）后，对颈部、胸部、腹部或骨盆进行非增强螺旋CT成像。结果：共定位PET-CT图像识别和定位55个病灶。在10名患者（31%），与正常的生理FDG摄取的变量的区域区分从附近的肿瘤病变的FDG的潜在摄取。改善定位在9例患者（共13个病灶，或24%）。结论：联合PET-CT图像出现更有效的比PET图像单独精确定位肿瘤性病变，并区分正常变异并置肿瘤性病变。
Purpose: To compare combined whole-body PET and CT images of different cancers with PET images alone.Materials and Methods: Thirty-two patients with known or possible cancers were examined using a combined positron emission tomographic (PET) and computed tomographic (CT) scanner. All data were acquired using this same combined scanner. After an injection of F-18 fluorodeoxyglucose (FDG), noncontrast helical CT imaging of the neck, chest, abdomen, or pelvis was performed. The spiral CT was followed by a PET scan covering the same axial extent as the CT.Results: Coregistered PET-CT images identified and localized 55 lesions. In 10 patients (31%), areas with variable amounts of normal physiologic FDG uptake were distinguished from potential uptake of FDG in a nearby neoplastic lesion. Improved localization was achieved in 9 patients (for a total of 13 lesions, or 24%).Conclusion: Combined PET-CT images appear more effective than PET images alone to localize precisely neoplastic lesions and to distinguish normal variants from juxtaposed neoplastic lesions.