Ventilation during early and late rapid-eye-movement sleep in normal humans.
Ventilation during early and late rapid-eye-movement sleep in normal humans.
复制标题
正常人早期和晚期快速眼动睡眠期间的通气。
DOI：
10.1152/jappl.1991.71.4.1201
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发表时间：
1991
期刊：
影响因子：
--
通讯作者：
Pack,AI
中科院分区：
文献类型：
--
作者：
Neilly,JB;Gaipa,EA;Maislin,G;Pack,AI
由于夜间连续的快速眼动（REM）睡眠周期持续时间更长，有更多的阶段性事件，晚期快速眼动睡眠期间的通气可能比早期发作时受到更大的影响。尽管眼动密度（EMD）在快速眼动睡眠晚期有所增加，但平均分钟通气量与快速眼动睡眠早期相比并未减少。随着EMD的增加，胸腔运动（胸腔平均吸气流量）的减少被呼吸频率的增加所抵消。除呼气时间外，EMD与特定通气成分之间的关系斜率从早期到后期REM睡眠期间没有显著变化。然而，在快速眼动睡眠后期减少通气时，发作次数有所增加。快速眼动睡眠后期通气模式的改变是由于快速眼动睡眠潜在性质的改变。然而，眼球运动时的通气反应是受试者特有的。在眼球运动爆发期间，一些受试者表现出胸腔平均吸气流量的大幅下降和呼吸频率的增加，而另一些人则表现出这些通气参数的微小变化。
Because successive rapid-eye-movement (REM) sleep periods in the night are longer in duration and have more phasic events, ventilation during late REM sleep might be more affected than in earlier episodes. Despite the increase in eye movement density (EMD) in late REM sleep, average minute ventilation was, however, not reduced compared with that in early REM sleep. Decreases in rib cage motion (mean inspiratory flow of the rib cage) in association with increasing EMD were offset by increments in respiratory frequency. Apart from expiratory time, there were no significant changes in the slopes of the relationships between EMD and specific ventilatory components, from early to late REM sleep periods. However, there was an increase in the number of episodes when ventilation was reduced during late REM sleep. Changes in ventilatory pattern during late REM sleep are due to changes in the underlying nature of REM sleep. The ventilatory response during eye movements is, however, subject specific. Some subjects exhibit large decrements in mean inspiratory flow of the rib cage and increments in respiratory frequency during bursts of eye movement, whereas other individuals demonstrate only small changes in these ventilatory parameters.