COVID-19 Vaccine in Pregnant and Lactating Women: A Review of Existing Evidence and Practice Guidelines.
COVID-19 Vaccine in Pregnant and Lactating Women: A Review of Existing Evidence and Practice Guidelines.
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DOI：
10.3390/idr13030064
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发表时间：
2021-07-31
影响因子：
3.2
通讯作者：
Pal S
中科院分区：
文献类型：
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作者：
Garg I;Shekhar R;Sheikh AB;Pal S
2019冠状病毒（COVID-19）造成了一场全球大流行，对人类生命、公共医疗系统和全球经济造成了毁灭性的影响。由于科学界的努力以及联邦政府与制药公司的合作，多种有效且安全的COVID-19疫苗以前所未有的速度开发出来。然而，持续将孕妇及哺乳期妇女排除于COVID抗病毒及疫苗试验之外，造成了在高风险人群中缺乏经验证据的矛盾。基于类似的既往疫苗、动物发育和生殖毒理学研究的经验，以及人类研究的初步结果，多个医疗保健专业咨询委员会（免疫实践咨询委员会、美国妇产科医师学院、母胎医学学会和母乳喂养医学学会）发布了支持孕妇和哺乳期妇女接种COVID-19疫苗的指南。在这篇文章中，我们总结了关于COVID-19疫苗在孕妇和哺乳期妇女中的有效性和安全性的现有数据，审查了疫苗犹豫的挑战，并包括对医疗保健提供者的建议。
Coronavirus 2019 (COVID-19) has created a global pandemic that is devastating human lives, public healthcare systems, and global economies. Multiple effective and safe COVID-19 vaccines have been developed at an unprecedented speed due to the efforts of the scientific community, and collaboration between the federal government and pharmaceutical companies. However, the continued exclusion of pregnant and lactating women from the COVID anti-viral and vaccine trials has created the paradox of a lack of empirical evidence in a high-risk population. Based on the experience of similar prior vaccines, animal developmental and reproductive toxicology studies, and preliminary findings from human studies, various healthcare professional advisory committees (Advisory Committee on Immunization Practices, American College of Obstetricians and Gynecologists, Society for Maternal-Fetal Medicine, and Academy of Breastfeeding Medicine) have issued guidance supporting COVID-19 vaccination in pregnant and lactating women. In this article, we summarize the available data on the efficacy and safety profile of COVID-19 vaccination in pregnant and lactating women, review the challenges of vaccine hesitancy, and include recommendations for healthcare providers.
影响因子：
4.2
作者：
Wang SV;Stefanini K;Lewis E;Newcomer SR;Fireman B;Daley MF;Glanz JM;Duffy J;Weintraub E;Kulldorff M
通讯作者：
Kulldorff M