Synthesis and properties of gem-(difluorocyclopropyl)amine derivatives of bicyclo[n.1.0]alkanes.
Synthesis and properties of gem-(difluorocyclopropyl)amine derivatives of bicyclo[n.1.0]alkanes.
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DOI：
10.1002/chin.200512046
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发表时间：
2004-11
期刊：
影响因子：
5.2
通讯作者：
I. Nowak;J. Cannon;M. Robins
中科院分区：
文献类型：
--
作者：
I. Nowak;J. Cannon;M. Robins
[反应：在衍生自环酮的烯胺存在下，二氟卡宾（类卡宾）的生成导致CF 2的全部插入以产生双环二氟环丙胺。这些加合物是非常弱的碱性，它们的热稳定性随它们的结构而显著变化。
[reaction: see text] Generation of difluorocarbene(carbenoid) in the presence of enamines derived from cyclic ketones results in overall insertion of CF2 to produce bicyclic difluorocyclopropylamines. These adducts are very weakly basic, and their thermal stabilities vary markedly with their structures.