Renal Resistive Index and Cardiovascular and Renal Outcomes in Essential Hypertension
Renal Resistive Index and Cardiovascular and Renal Outcomes in Essential Hypertension
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DOI：
10.1161/hypertensionaha.112.196717
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发表时间：
2012-09-01
期刊：
影响因子：
8.3
通讯作者：
Kawano, Yuhei
中科院分区：
文献类型：
--
作者：
Doi, Yohei;Iwashima, Yoshio;Kawano, Yuhei
Increased renal restive index (RI) measured using Doppler ultrasonography has been shown to correlate with the degree of renal impairment in hypertensive patients. We investigated the prognostic role of RI in cardiovascular and renal outcomes. A total of 426 essential hypertensive subjects (mean age, 63 years; 50% female) with no previous cardiovascular disease were included in this study. Renal segmental arterial RI was measured by duplex Doppler ultrasonography. During follow-up (mean, 3.1 years), 57 participants developed the primary composite end points including cardiovascular and renal outcomes. In multivariate Cox regression analysis, RI was an independent predictor of worse outcome in total subjects (hazard ratio, 1.71 for 1 SD increase), as well as in patients with estimated glomerular filtration rate (eGFR)
