HYDRATION AND SOLUTION STRUCTURE OF NUCLEIC-ACIDS

HYDRATION AND SOLUTION STRUCTURE OF NUCLEIC-ACIDS
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DOI:
10.1016/0959-440x(95)80094-8
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发表时间:
1995-06-01
影响因子:
6.8
通讯作者:
LEROY, JL
LEROY, JL
中科院分区:
生物学2区
文献类型:
--
作者:
KOCHOYAN, M;LEROY, JL

文献摘要

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在最近新的DNA结构的启示中,特别令人感兴趣的是发现端粒和着丝粒中发现的重复DNA序列的两条链可能采用替代构象。高清晰度核磁共振研究产生了水分子与核酸相互作用的停留时间的信息。更好地了解水合水的停留时间可能有助于评估其对核酸结构的贡献。
Of particular interest among the revelations from recent new DNA structures is the finding that both strands of the repeated DNA sequences found in telomeres and centromeres may adopt alternative conformations. High-definition NMR studies yielded information on the residence time of the water molecules interacting with nucleic acids. A better knowledge of the residence time of the hydration water may be useful in assessing its contribution to nucleic acid structure.