FUNGAL KERATITIS IN SAUDI-ARABIA

FUNGAL KERATITIS IN SAUDI-ARABIA
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DOI:
10.1007/bf00158257
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发表时间:
1992-01-01
影响因子:
1.4
通讯作者:
TABBARA, KF
TABBARA, KF
中科院分区:
医学4区
文献类型:
--
作者:
KHAIRALLAH, SH;BYRNE, KA;TABBARA, KF

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我们共研究了沙特阿拉伯27例真菌性角膜炎。9例患者有外伤史,6例患者既往使用过局部类固醇。大多数患者的发病时间为秋季和春季。真菌性角膜炎最常见的原因是曲霉,从11例(41%)病例中分离出来。11株分离物中8株为黄曲霉。其他引起角孢菌病的原因包括:镰刀菌、念珠菌和无菌菌丝。所有患者均接受抗真菌治疗,18例患者需要手术干预。11例患者视力改善,4例患者视力不变,6例患者治疗后视力恶化。(6例患者未能返回随访。)27例患者中有4例发生真菌性眼内炎。曲霉菌的高流行率可能是由于曲霉菌的孢子可以在沙特阿拉伯炎热和干燥的天气中存活。
We studied a total of 27 cases of fungal keratitis is Saudi Arabia. History of trauma was found in 9 patients, and previous use of topical steroids in 6 patients. In the majority of patients the onset of the disease was in fall and spring. The most frequent cause of fungal keratitis was found to be Aspergillus spp., and these were isolated from 11 cases (41%). Eight of the 11 isolates were Aspergillus flavus. Other causes of keratomycosis included: Fusarium, Candida, and Mycelia sterilia. All patients were treated with antifungal therapy and 18 patients required surgical intervention. Vision improved among 11 patients, remained the same in 4 patients, and deteriorated after treatment in 6 patients. (6 patients failed to return for follow-up.) Four of the 27 patients developed fungal endophthalmitis. The high prevalence of Aspergillus spp. may be due to the fact that spores of Aspergillus can survive the hot and dry weather of Saudi Arabia.