Identifying patterns of retention in care and viral suppression using latent class analysis among women living with HIV in Florida 2015-2017.
Identifying patterns of retention in care and viral suppression using latent class analysis among women living with HIV in Florida 2015-2017.
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DOI：
10.1080/09540121.2020.1771264
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发表时间：
2021-01
期刊：
影响因子：
1.7
通讯作者：
Trepka MJ
中科院分区：
文献类型：
--
作者：
Dawit R;Sheehan DM;Gbadamosi SO;Fennie KP;Li T;Curatolo D;Maddox LM;Spencer EC;Trepka MJ
研究目的是将新诊断的艾滋病毒妇女分为持续护理模式（≥2次艾滋病毒护理访问间隔≥3个月）和病毒抑制模式，并确定与班级成员相关的因素。采用佛罗里达州HIV/AIDS监测数据进行潜类分析，对女性进行分类，并采用多项回归比较人口统计学和临床因素对类别成员的患病率。根据模型拟合参数选择4个类别：（1类）持续保留和抑制（保留和抑制的概率小于90%），（2类）不持续保留或抑制（保留和抑制的概率≤10%），（3类）持续保留和抑制，（4类）持续保留和抑制的减少。每个班级的女性比例分别为48.6%、24.9%、14.3%和12.2%。25-34岁的女性与35-49岁的女性相比，注射吸毒方式暴露，美国出生，诊断后三个月未接受护理的女性属于持续保留和抑制类的患病率较低。研究结果可能有助于定制和有针对性的干预措施，以增加持续接受护理和病毒抑制的妇女的患病率。
The study objective was to classify women with newly diagnosed HIV into patterns of retention in care (≥2 HIV care visits ≥3 months apart) and viral suppression over time and identify factors associated with class membership. Florida HIV/AIDS surveillance data were used to conduct Latent Class Analysis to classify women into patterns, and multinomial regression was used to compare prevalence of class membership by demographic and clinical factors. Four classes were selected based on model fit parameters: (Class 1) consistently retained and suppressed (>90% probability of being retained and suppressed), (Class 2) not consistently retained or suppressed (≤10% probability of being retained and suppressed), (Class 3) increasingly retained and suppressed, and (Class 4) decreasingly retained and suppressed. The proportion of women in each class was 48.6%, 24.9%, 14.3%, and 12.2%, respectively. Women aged 25–34 compared to 35-49 years old, injection drug use mode of exposure, US born, and not linked to care three months post diagnosis had a lower prevalence of belonging to the consistently retained and suppressed class. Findings may be useful in tailoring and targeting interventions to increase the prevalence of women who are consistently retained in care and virally suppressed.
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