MRI and CT in the diagnosis of coronary artery disease: indications and applications.
MRI and CT in the diagnosis of coronary artery disease: indications and applications.
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DOI：
10.1007/s13244-010-0049-0
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发表时间：
2011-02
影响因子：
4.7
通讯作者：
Wintersperger, Bernd J
中科院分区：
文献类型：
--
作者：
Nikolaou, Konstantin;Alkadhi, Hatem;Bamberg, Fabian;Leschka, Sebastian;Wintersperger, Bernd J
近年来，心脏计算机断层扫描（CT）和心脏磁共振成像（MRI）的技术进步和改进引起了人们对这些技术在疑似冠状动脉疾病（CAD）患者的非侵入性检查中的潜在临床作用以及这些新兴成像技术的正确患者选择的兴趣。在主要检测或排除重大CAD时，例如，在患有非特异性胸部疾病的患者中，以及在患有已知CAD或晚期CAD的患者中，CT和MRI都具有特定的优势。本文就无创性MR和CT在冠心病诊断中的应用进行综述。第一部分描述了对比增强无创CT冠状动脉造影（CTCA）的临床价值，包括CTCA排除或检测可能需要血管成形术介入治疗的冠状动脉狭窄的重大CAD的诊断准确性，以及冠状动脉血管壁的潜在有价值的信息。在第二部分中，将强调CT用于心肌存活性和灌注成像的潜力。在第三部分和最后一部分，心脏MRI在CAD患者中的应用范围将被概述。
In recent years, technical advances and improvements in cardiac computed tomography (CT) and cardiac magnetic resonance imaging (MRI) have provoked increasing interest in the potential clinical role of these techniques in the non-invasive work-up of patients with suspected coronary artery disease (CAD) and correct patient selection for these emerging imaging techniques. In the primary detection or exclusion of significant CAD, e.g. in the patient with unspecific thoracic complaints, and also in patients with known CAD or advanced stages of CAD, both CT and MRI yield specific advantages. In this review, the major aspects of non-invasive MR and CT imaging in the diagnosis of CAD will be discussed. The first part describes the clinical value of contrast-enhanced non-invasive CT coronary angiography (CTCA), including the diagnostic accuracy of CTCA for the exclusion or detection of significant CAD with coronary artery stenoses that may require angioplastic intervention, as well as potentially valuable information on the coronary artery vessel wall. In the second section, the potential of CT for the imaging of myocardial viability and perfusion will be highlighted. In the third and final part, the range of applications of cardiac MRI in CAD patients will be outlined.