Metal-enhanced fluorescence of OG-488 doped in Au@SiO2 core–shell nanoparticles
Metal-enhanced fluorescence of OG-488 doped in Au@SiO2 core–shell nanoparticles
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DOI：
10.1016/j.matlet.2013.09.021
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发表时间：
2013-12
影响因子：
3
通讯作者：
Cuiyan Li;Jiefang Zhu
中科院分区：
文献类型：
--
作者：
Cuiyan Li;Jiefang Zhu
单分散的金核二氧化硅壳层(Au@SiO_2)纳米粒子在金属增强荧光(MEF)方面显示出巨大的应用潜力。在硅壳中掺杂了一种新型的荧光团--俄勒冈绿488-异硫氰酸酯(OG-488)。金纳米粒子增强了OG-488的荧光，而硅壳用于控制OG-488与金表面的距离，以缓解荧光猝灭。研究了不同壳层厚度(15 nm~50 nm)和不同金核直径(40 nm、60 nm和80 nm)下Au@SiO2纳米粒子的荧光增强作用。与不含Au核的OG-488掺杂二氧化硅微球相比，Au@SiO2纳米粒子的荧光发射强度最大提高了35倍。
Monodisperse Au-core silica-shell (Au@SiO2) nanoparticles demonstrated a great potential for the application of metal-enhanced fluorescence (MEF). The silica shell was doped with a novel fluorophore, Oregon Green 488-isothiocyanate (OG-488). The fluorescence of OG-488 was enhanced by Au nanoparticle core, while the silica shell was used to control the distance between OG-488 and Au surface to alleviate fluorescence quenching. The fluorescence enhancement by Au@SiO2nanoparticles was investigated by varying SiO2shell thickness (from 15 nm to 50 nm) and Au core diameter (40 nm, 60 nm and 80 nm). Compared with OG-488 doped silica spheres without Au core, the Au@SiO2nanoparticles maximally gave 35-fold stronger fluorescence emission.