Pharmacological Treatment of Neonatal and Juvenile Mice to Study Spermatogenesis.
Pharmacological Treatment of Neonatal and Juvenile Mice to Study Spermatogenesis.
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DOI:
10.1007/978-1-0716-3139-3_13
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发表时间:
2023
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The delivery, to newborn and juvenile mice, of drugs and other compounds that manipulate the physiology or cellular/molecular state -e.g., by activating or inhibiting signaling pathways) is a powerful, yet under-utilized approach to studying spermatogenesis. Here, we provide detailed protocols we have optimized in our laboratory for safely and effectively feeding and injecting mice and discuss troubleshooting approaches.