Metal-free one-pot synthesis of 1,3-diazaheterocyclic compounds via I2-mediated oxidative C-N bond formation
Metal-free one-pot synthesis of 1,3-diazaheterocyclic compounds via I2-mediated oxidative C-N bond formation
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DOI：
10.1039/c5ra11262a
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发表时间：
2015-01-01
期刊：
影响因子：
3.9
通讯作者：
Chang, Junbiao
中科院分区：
文献类型：
--
作者：
Tian, Xianhai;Song, Lina;Chang, Junbiao
研究了一种由碘-2介导的含二氨基的底物与醛通过氧化形成C-N键的一锅成环反应。这种通用且环境友好的合成方法提供了容易获得各种1，3-二氮杂环化合物的途径，包括喹唑啉酮、苯并咪唑和环脒。
A one-pot I-2-mediated annulation reaction of substrates containing diamino groups and aldehydes has been developed via oxidative C-N bond formation. This general and environmentally benign synthetic approach provides facile access to a variety of 1,3-diazaheterocyclic compounds, including quinazolinones, benzimidazoles, and cyclic amidines.