Response regulator DegU of Listeria monocytogenes controls temperature-responsive flagellar gene expression in its unphosphorylated state
Response regulator DegU of Listeria monocytogenes controls temperature-responsive flagellar gene expression in its unphosphorylated state
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DOI：
10.1128/jb.00258-08
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发表时间：
2008-07-01
影响因子：
3.2
通讯作者：
Beier, Dagmar
中科院分区：
文献类型：
--
作者：
Mauder, Norman;Williams, Tatjana;Beier, Dagmar
我们证明，在单核细胞增生李斯特菌，温度响应的转录控制鞭毛基因不依赖于保守的磷酸化位点（D55）的反应调节DegU的接收域的磷酸化。此外，适当控制DegU调节的基因参与乙醇耐受性和毒力是独立的受体磷酸化。
We demonstrate that in Listeria monocytogenes, temperature-responsive transcriptional control of flagellar genes does not rely on the phosphorylation of the conserved phosphorylation site (D55) in the receiver domain of response regulator DegU. Furthermore, proper control of DegU-regulated genes involved in ethanol tolerance and virulence is independent of receiver phosphorylation.