Secondary syphilitic uveitis.
Secondary syphilitic uveitis.
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二期梅毒性葡萄膜炎。
DOI：
10.1016/0002-9394(81)90773-x
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发表时间：
1981
影响因子：
4.2
通讯作者：
Hay,PB
中科院分区：
文献类型：
--
作者：
Belin,MW;Baltch,AL;Hay,PB
1例二期梅毒患者血清和脑脊液检查均阳性。荧光抗体暗视野试验证明在水螺旋体（梅毒螺旋体）。有二期梅毒的临床体征，包括手掌皮肤病变和前额秃顶，以及双侧鼻侧高度视野丧失。分散的、蜡样的、黄白色视网膜病变变得越来越色素沉着，后来向前迁移到玻璃体腔中。患者接受了大量青霉素（总剂量为4.4亿单位）和丙磺舒治疗。视力改善至R.E.：6/9（20/30）和L.E.：6/12（20/40）例炎症反应消失。治疗结束八周后的第二次水龙头通过荧光抗体检测显示没有螺旋体。
A patient with secondary syphilis had positive serum and cerebroespinal fluid findings. Fluorescent-antibody darkfield testing demonstrated spirochetes (Treponema pallidum) in the aqueous. There were clinical signs of secondary syphilis, including palmar skin lesions and frontal balding, and bilateral nasal altitudinal visual field loss. The discrete, waxy, yellow-white retinal lesions became increasingly pigmented and later migrated anteriorly into the vitreous chamber. The patient was treated with large amounts of penicillin (total dosage, 440 million units) and probenecid. Visual acuity improved to R.E.: 6/9 (20/30) and L.E.: 6/12 (20/40) and the inflammatory reaction disappeared. A second aqueous tap eight weeks after therapy ended showed no spirochetes by fluorescent-antibody testing.