Spectrum and outcome of congestive heart failure in a hospitalized population.
Spectrum and outcome of congestive heart failure in a hospitalized population.
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住院人群充血性心力衰竭的谱系和结果。
DOI：
10.1016/0002-8703(93)90414-5
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发表时间：
1993
影响因子：
4.8
通讯作者：
F. Waagstein
中科院分区：
文献类型：
--
作者：
B. Andersson;F. Waagstein
目前关于普通人群充血性心力衰竭（CHF）发生频率和原因的研究很少。在居住着164万人口的瑞典西部，进行了一项回顾性调查。该地区所有医院均检查了 16 岁至 65 岁 CHF 患者的所有医院记录。研究期间，2711 名患者符合 CHF 或心肌病的标准。对患者进行为期 37 ± 28 个月的监测。心力衰竭最常见的原因是冠状动脉疾病（IHD）（40%）。其他常见原因包括高血压（17%）、瓣膜病（13%）、酒精（11%）、糖尿病（10%）和全身性疾病（10%）。男性与IHD、酒精和扩张型心肌病呈正相关；女性与全身性疾病、瓣膜性心脏病和糖尿病有关。在最年轻（16 至 30 岁）和最年长（61 至 65 岁）年龄组中，每 100,000 人中需要住院治疗的 CHF 发病率分别为 1.2 至 263 名男性和 1.1 至 129 名女性。 5年生存率为50%。使用 Cox 生存比例风险模型进行的原因分析表明，年龄、IHD、酒精和糖尿病是死亡率的独立且有力的预测因素 (p<0.001)。死亡方式为进行性心力衰竭（54%）和猝死（26%）。我们得出的结论是，即使在年轻人群中，CHF 患者的预后仍然很差。 CHF最常见的原因是IHD，其次是高血压。
There are very few contemporary studies on the frequency and cause of congestive heart failure (CHF) in a general population. In western Sweden, inhabited by 1.64 million people, a retrospective survey was performed. All hospital records of patients with CHF, ages 16 through 65 years, were examined in all hospitals in the region. During the study period 2711 patients fulfilled the criteria for CHF or cardiomyopathy. Patients were monitored for 37 ± 28 months. The most common cause of heart failure was coronary artery disease (IHD) (40%). Other common causes were hypertension (17%), valvular disease (13%), alcohol (11%), diabetes mellitus (10%), and systemic diseases (10%). There were positive correlations between the male sex and IHD, alcohol, and dilated cardiomyopathy; the female sex was associated with systemic diseases, valvular heart disease, and diabetes. The incidence of CHF requiring hospitalization per 100,000 in the population was 1.2 to 263 men and 1.1 to 129 women, in the youngest (age 16 to 30 years) and oldest (61 to 65 years) age groups, respectively. The 5-year survival rate was 50%. Analysis of causes performed with Cox's proportional hazards model for survival showed that age, IHD, alcohol, and diabetes were independent and powerful predictors of mortality (p< 0.001). The mode of death was progressive heart failure in 54% and sudden death in 26%. We concluded that the prognosis in patients with CHF was still very poor, even among this young population. The most common cause of CHF was IHD, and the second was hypertension.
影响因子：
158.5
作者：
COHN, JN;LEVINE, TB;RECTOR, T
通讯作者：
RECTOR, T