Central Nervous System and Computation

Central Nervous System and Computation
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中枢神经系统和计算

DOI:
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发表时间:
2011
期刊:
The Quarterly review of biology
影响因子:
--
通讯作者:
L. Agnati
L. Agnati
中科院分区:
--
文献类型:
--
作者:
D. Guidolin;G. Albertin;M. Guescini;K. Fuxe;L. Agnati

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计算系统在神经科学中有很多用途。例如,它们可用于构建大脑结构和激活图,或以数学方式描述大脑过程。此外,他们激发了一种强大的大脑功能理论,其中大脑被视为一个以内在计算活动为特征的系统或“计算信息处理器”。尽管许多神经科学家相信神经系统确实可以执行计算,但有些人对计算主义更加谨慎或拒绝。那么,大脑真的会计算吗?回答这个问题需要明确计算的定义,该定义能够在计算的物理系统和不计算的系统之间划清界限,以便我们能够辨别大脑(或其一部分)可能落在这条线的哪一边。为了阐明计算过程在大脑功能中的作用,将从最近提出的计算概念分类学的角度总结可用的神经生物学数据,目的是确定哪些大脑过程可以被视为计算过程。新的图像显示大脑是一个非常奇特的系统,其中真正的计算特征与非计算动态过程协同作用,导致在来自环境和生物体其他部分的外部刺激的作用下持续的自组织和重塑。
Computational systems are useful in neuroscience in many ways. For instance, they may be used to construct maps of brain structure and activation, or to describe brain processes mathematically. Furthermore, they inspired a powerful theory of brain function, in which the brain is viewed as a system characterized by intrinsic computational activities or as a “computational information processor.” Although many neuroscientists believe that neural systems really perform computations, some are more cautious about computationalism or reject it. Thus, does the brain really compute? Answering this question requires getting clear on a definition of computation that is able to draw a line between physical systems that compute and systems that do not, so that we can discern on which side of the line the brain (or parts of it) could fall. In order to shed some light on the role of computational processes in brain function, available neurobiological data will be summarized from the standpoint of a recently proposed taxonomy of notions of computation, with the aim of identifying which brain processes can be considered computational. The emerging picture shows the brain as a very peculiar system, in which genuine computational features act in concert with noncomputational dynamical processes, leading to continuous self-organization and remodeling under the action of external stimuli from the environment and from the rest of the organism.
非洲爪蟾肌肉细胞电场诱导的乙酰胆碱受体簇细胞内蛋白质的定位。
DOI: 10.1242/jcs.94.1.73
发表时间: 1989
影响因子: 4
作者:
Rochlin,MW;Peng,HB
通讯作者: Peng,HB
涉及通过大脑细胞外空间传输化学信号的问题。
DOI: --
发表时间: 1988
期刊: Acta morphologica Neerlando-Scandinavica
影响因子: --
作者:
Nicholson,C
通讯作者: Nicholson,C
DOI: 10.1126/science.283.5400.381
发表时间: 1999-01-15
期刊: SCIENCE
影响因子: 56.9
作者:
Bhalla, US;Iyengar, R
通讯作者: Iyengar, R