APPLICATION OF AN IDEALIZED MODEL TO MORPHOMETRY OF MAMMALIAN TRACHEOBRONCHIAL TREE

APPLICATION OF AN IDEALIZED MODEL TO MORPHOMETRY OF MAMMALIAN TRACHEOBRONCHIAL TREE
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DOI:
10.1002/ar.1091900202
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发表时间:
1978-01-01
期刊:
影响因子:
--
通讯作者:
RAABE, OG
RAABE, OG
中科院分区:
医学4区
文献类型:
--
作者:
PHALEN, RF;YEH, HC;RAABE, OG

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气管支气管气道的定量解剖描述(形态测量)在许多应用中都很重要,包括准备描述肺部空气中颗粒的气流模式和沉积模式的成功数学模型。形态测量数据还可用于比较解剖学研究以及描述器官的正常和患病状态。通过使用气管支气管气道分支的理想化模型来帮助收集此类数据。使用由 3 个相连的管状部分组成的模型对几种哺乳动物的肺部进行形态测量。形态测量模型唯一地定义了每个分支段的识别号、分支角度、气道段长度和直径、段对重力的倾斜度以及每个段的肺泡化程度。该模型旨在与计算机数据处理兼容,明确且现实,但灵活,以便可以对异常解剖结构进行分类和记录。描述气管支气管气道结构随深度变化的形态测量数据以人类、狗、大鼠和仓鼠气道复制模型上的解剖测量图形表示的形式呈现。这些分布简明、定量和特征性地描述了每个物种的气管支气管的解剖特征。
Quantitative anatomical descriptions (morphometry) of the tracheobronchial airways are of importance in many applications including the preparation of successful mathematical models describing airflow patterns and deposition patterns of airborne particles in the lung. Morphometric data are also useful in studies of comparative anatomy and in describing normal and diseased states of an organ. The collection of such is aided by the use of idealized models of airway branches of the tracheobronchial airways. Morphometric measurements from the lungs of several mammalian species are presented using a model that consists of 3 connected tubular segments. The morphometric model uniquely defines an identification number of each branch segment, a branching angle, an airway segment length and diameter, an inclination of a segment to gravity and the degree of alveolarization of each segment. Designed to be compatible with computerized data handling, the model is unambiguous and realistic, but flexible so that anomalous anatomical structures can be classified and noted. Morphometric data describing the variation of structure with depth in the tracheobronchial airways are presented in the form of graphical representations of anatomical measurements on replica casts of the human, dog, rat and hamster airways. These distributions describe the anatomical character of the tracheobronchial airways concisely, quantitatively and characteristically for each species.