Quantitative Analysis of Apatite Formation on Titanium and Zirconia in a Simulated Body Fluid Solution Using the Quartz Crystal Microbalance Method
Quantitative Analysis of Apatite Formation on Titanium and Zirconia in a Simulated Body Fluid Solution Using the Quartz Crystal Microbalance Method
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使用石英晶体微天平法定量分析模拟体液溶液中钛和氧化锆上磷灰石的形成
DOI：
10.1155/2017/7928379
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发表时间：
2017
影响因子：
--
通讯作者：
Hayakawa T.
中科院分区：
文献类型：
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作者：
Yoshida E;Hayakawa T.
通过检查模拟体液（SBF）中材料表面的磷灰石形成来评价材料的骨结合能力。部分稳定氧化锆（ZrO 2）是目前有吸引力的替代钛（Ti）植入物;然而，没有定量分析的钛和ZrO 2之间的磷灰石形成在SBF的报告。在本研究中，我们定量评估磷灰石形成到Ti或ZrO 2在SBF使用27 MHz的石英晶体微天平法（QCM）。在QCM测量中，磷灰石的形成被检测为在Ti或ZrO 2传感器中的频率降低。在注入SBF后，在约1小时观察到Ti的频率降低，在约2小时观察到ZrO 2传感器的频率降低。这表明Ti传感器显示出比ZrO 2更快的磷灰石形成。在SBF中磷灰石形成24小时后，Ti和ZrO 2传感器之间的磷灰石形成量没有显著差异。结果表明，在模拟体液中，钛表面磷灰石的生成速度明显快于ZrO 2表面。与ZrO 2相比，更快的磷灰石形成可以预测Ti上更快的骨形成起始。
The bone‐bonding ability of a material is evaluated by examining apatite formation on its surface in simulated body fluid (SBF). Partially stabilized zirconia (ZrO2) is currently attractive as an alternative to titanium (Ti) implants; however, no quantitative analysis of apatite formation between Ti and ZrO2in SBF has been reported. In the present study, we quantitatively evaluated apatite formation onto Ti or ZrO2in SBF using the 27 MHz quartz crystal microbalance method (QCM). In the QCM measurements, apatite formation was detected as a frequency decrease in the Ti or ZrO2sensor. Frequency decreases were observed at around 1 hour for Ti and at around 2 hours for the ZrO2sensor after the injection of SBF. This revealed that the Ti sensor showed faster apatite formation than ZrO2. There was no significant difference in the amounts of apatite formation between the Ti and ZrO2sensors after 24 hours of apatite formation in SBF. In conclusion, the present quantitative study using QCM revealed that apatite formation on the Ti surface in the SBF was obviously faster than that on the ZrO2surface. Faster apatite formation may predict faster initiation of bone formation on Ti compared with ZrO2.