Antiviral efficacy of personal care formulations against Severe Acute Respiratory Syndrome Coronavirus 2

Antiviral efficacy of personal care formulations against Severe Acute Respiratory Syndrome Coronavirus 2
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DOI:
10.1016/j.idh.2020.09.003
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发表时间:
2021-01-12
影响因子:
3.5
通讯作者:
Yekhe, Ashish Shrikant
Yekhe, Ashish Shrikant
中科院分区:
其他
文献类型:
--
作者:
Mukherjee, Sayandip;Vincent, Carol K.;Yekhe, Ashish Shrikant

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背景:保持良好手部卫生等非治疗性干预措施仍然是预防 SARS-CoV-2 和其他新兴呼吸道病毒的主要措施。方法:我们使用国际公认的标准化方案,在与用户相关的接触时间点和产品稀释度下,评估了一系列市售个人护理产品(包括肥皂、洗手液和酒精类洗手液)对 SARS-CoV-2 临床分离株的抗病毒功效。结果:所有测试产品的结果为 3 至 3 SARS-CoV-2 滴度减少 4 个对数。结论:我们的数据再次证实了全球公共卫生当局的建议,即适当的手部卫生可以显着降低 SARS-CoV-2 病毒载量,这可能会限制传染病的传播。 (C) 2020 作者。由 Elsevier B.V. 代表澳大利亚感染预防与控制学院出版。
Background: Non-therapeutic interventions such as practicing good hand hygiene continue to be the mainstay of protection from SARS-CoV-2 and other emerging respiratory viruses.Methods: We have evaluated a range of commercially available personal care products including soaps, handwash liquids and alcohol-based hand sanitizers for antiviral efficacy against a clinical isolate of SARS-CoV-2 using internationally accepted standardized protocols at user-relevant contact time-points and product dilutions.Results: All the tested products resulted in 3 to 4 log reduction of SARS-CoV-2 titer.Conclusion: Our data re-affirms recommendations by global public health authorities that proper hand hygiene can reduce SARS-CoV-2 viral load significantly which should likely limit spread of the contagion. (C) 2020 The Authors. Published by Elsevier B.V. on behalf of Australasian College for Infection Prevention and Control.