Fatty acids in arbuscular mycorrhizal fungi are synthesized by the host plant
Fatty acids in arbuscular mycorrhizal fungi are synthesized by the host plant
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DOI：
10.1126/science.aan0081
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发表时间：
2017-06-16
期刊：
影响因子：
56.9
通讯作者：
Eastmond, Peter J.
中科院分区：
文献类型：
--
作者：
Luginbuehl, Leonie H.;Menard, Guillaume N.;Eastmond, Peter J.
植物与丛枝菌根真菌形成有益的联系，促进从土壤中获取养分。作为回报，真菌从植物中接收有机碳。转录因子RAM1（丛枝菌根1所需）对于这种共生至关重要，我们证明它对于诱导在容纳真菌丛枝的植物细胞中表达的脂质生物合成途径是必要且充分的。脂质从植物转移到菌根真菌（脂肪酸营养缺陷型），这种脂质输出需要 3-磷酸甘油酰基转移酶 RAM2（RAM1 的直接靶点）。我们的工作表明，除了糖之外，脂质是传递给真菌的有机碳的主要来源，这对于真菌脂质的生产是必需的。
Plants form beneficial associations with arbuscular mycorrhizal fungi, which facilitate nutrient acquisition from the soil. In return, the fungi receive organic carbon from the plants. The transcription factor RAM1 (REQUIRED FOR ARBUSCULAR MYCORRHIZATION 1) is crucial for this symbiosis, and we demonstrate that it is required and sufficient for the induction of a lipid biosynthetic pathway that is expressed in plant cells accommodating fungal arbuscules. Lipids are transferred from the plant to mycorrhizal fungi, which are fatty acid auxotrophs, and this lipid export requires the glycerol-3-phosphate acyltransferase RAM2, a direct target of RAM1. Our work shows that in addition to sugars, lipids are a major source of organic carbon delivered to the fungus, and this is necessary for the production of fungal lipids.