Residential proximity fine particles related to allergic sensitisation and asthma in primary school children

Residential proximity fine particles related to allergic sensitisation and asthma in primary school children
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DOI:
10.1016/j.rmed.2007.02.022
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发表时间:
2007-08-01
影响因子:
4.3
通讯作者:
Charpin, Denis
Charpin, Denis
中科院分区:
医学3区
文献类型:
--
作者:
Annesi-Maesano, Isabella;Moreau, David;Charpin, Denis

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背景资料:细颗粒物与过敏有关的实验和流行病学数据使用了固定地点监测站提供的汇总数据或浓度,这可能导致对个人暴露于空气污染的错误分类。方法:采用半个体设计,对5338名学龄儿童哮喘和变态反应的个体资料进行关联分析(10.4 +/- 0.7岁)在法国6个城市的108所随机选择的学校上学,对PM2.5(空气动力学直径的细颗粒物)浓度的影响
Background: Fine particulate matter has been linked to allergies by experimental and epidemiological data having used aggregated data or concentrations provided by fixed-site monitoring stations, which may have led to misclassification of individual exposure to air pollution.Methods: A semi-individual design was employed to relate individual data on asthma and allergy of 5338 school children (10.4 +/- 0.7 years) attending 108 randomly chosen schools in 6 French cities to the concentrations of PM2.5 (fine particles with aerodynamic diameter